1. KSM-66® Ashwagandha (Withania somnifera)
Chandrasekhar K et al. (2012). A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of Ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med. 34(3): 255–262.
Lopresti AL et al. (2019). The effects of ashwagandha (Withania somnifera) on cognitive functioning in adults: A systematic review of randomized controlled trials. J Diet Suppl.
2. Synapsa® Bacopa Monnieri
Stough C et al. (2001). The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects. Psychopharmacology (Berl). 156(4): 481–484.
Roodenrys S et al. (2002). Chronic effects of Brahmi (Bacopa monnieri) on human memory. Neuropsychopharmacology. 27(2): 279–281.
3. Suntheanine® (L-Theanine)
Hidese S et al. (2019). Effects of L-theanine on stress-related symptoms and cognitive functions in healthy adults: A randomized controlled trial. Nutrients. 11(10): 2362.
Kimura K et al. (2007). L-theanine reduces psychological and physiological stress responses. Biol Psychol. 74(1): 39–45.
4. Magtein® (Magnesium L-Threonate)
Slutsky I et al. (2010). Enhancement of learning and memory by elevating brain magnesium. Neuron. 65(2): 165–177.
Liu G et al. (2016). Magnesium L-threonate prevents and restores memory deficits associated with neuropathic pain by inhibition of TNF-α. Neurobiol Aging. 41: 24–37.
5. Gotu Kola (Centella asiatica)
Wattanathorn J et al. (2008). Evaluation of the effect of Centella asiatica on physical fatigue and cognitive functions. Food Chem Toxicol. 46(7): 2741–2748.
Gray NE et al. (2016). Centella asiatica: Phytochemistry and mechanisms of neuroprotection and cognitive enhancement. Phytochem Rev. 15: 161–181.
6. Jatamansi (Nardostachys jatamansi)
Sharma V et al. (2015). Effect of Nardostachys jatamansi on cognitive impairment induced by chronic fatigue syndrome. Int J Green Pharm.
Joshi H et al. (2007). Antianxiety activity of Nardostachys jatamansi DC in mice. J Ethnopharmacol. 109(2): 232–236.
7. Shankhpushpi (Convolvulus pluricaulis)
Choudhary N et al. (2012). Neuropharmacological effects of Convolvulus pluricaulis: An Ayurvedic herb. Int J Green Pharm.
Singh RH, Udupa KN. (1972). Clinical and experimental studies on Shankhpushpi. J Res Ind Med. 7(1): 1–8.
8. PharmaGABA® (Gamma-Aminobutyric Acid)
Abdou AM et al. (2006). Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans. Biofactors. 26(3): 201–208.
Yoto A et al. (2012). Effects of GABA on mood and sleep: A randomized, placebo-controlled study. Biofactors. 38(4): 238–243.
📄 Additional Notes:
All referenced studies are either randomized controlled trials (RCTs), systematic reviews, or peer-reviewed clinical research.
Ingredient trademarks like KSM-66®, Magtein®, Suntheanine®, PharmaGABA®, and Synapsa® have been studied independently and validated for cognitive and emotional health benefits.
